The right coronary artery or RCA travels originates above the right portion of the aortic valve and runs in the groove that separates the right atrium from the right ventricle, as it moves towards the bottom or inferior portion of the heart.

    The acute marginal coronary artery is given off in the proximal or early course of the artery. While the terminal or distal portion of the RCA gives off the posterior descending artery or PDA. The PDA runs in the bottom of the heart in a groove that separates the left and right ventricles, as it supplies branches to the lower portion of the septum (partition between the two ventricles. In 15% of cases, RCA is "non-dominant" and the Circ supplies the PDA branch.

    The RCA also supplies the postero-lateral artery or PLA to the lower back portion of the left ventricle and the right ventricular branch to the right ventricle.